NEJM Evidence PDF 2023
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Exclusive collection from NEJM Evidence featuring 6 confirmatory multi-year follow-ups of original research breakthroughs.

Each of the NEJM Evidence articles in this collection clarifies and builds on current medical evidence - to identify something not previously considered, to confirm current clinical practices thereby reinforcing clinical practice, or to create dialog around where more evidence and study is required.

This selection of confirmatory trials also features some of the original research breakthroughs, many of which were published in the New England Journal of Medicine.

Not only does this collection feature the NEJM Evidence Original Article abstracts and their accompanying Editorials, but also any of the associated New England Journal of Medicine Original Article abstracts.


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Inside this collection, discover studies on:

  • Overall Survival and Response with Nivolumab and Relatlimab in Advanced Melanoma
  • Long-Term Benefits from Early Antiretroviral Therapy Initiation in HIV Infection
  • Patient-Reported Outcomes 12 Years after Localized Prostate Cancer Treatment
  • Long-Term Outcomes of Adjuvant Denosumab in Breast Cancer
  • And more...

NEJM Evidence is a place for investigators — at all stages of research careers — and clinicians — whether in training now or in practice for decades — to come together to learn about advances in medicine and clinical trial design. The original research that NEJM Evidence publishes falls along the full spectrum of human investigation — from first-in-human studies that offer insight into the safety and potential efficacy of novel therapeutics to the late-stage confirmatory trials that solidify the evidence base that forms the foundation of clinical practice.

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