A t the end of each year, our editors review the research published in the New England Journal of Medicine and select a number of the most clinically important studies to highlight in the annual Notable Articles collection. This year's collection features 12 practice-changing studies that are improving patient care and outcomes.
Inside this PDF collection, you will find article abstracts, Research Summaries, and accompanying Editorials from the selected studies, plus a letter from, Eric J. Rubin, M.D., Ph.D., Editor-in-Chief.
Featured studies include:
- PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer
- Biologic and Clinical Efficacy of LentiGlobin for Sickle Cell Disease
- Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19
- Calorie Restriction with or without Time-Restricted Eating in Weight Loss
- Two Phase 3 Trials of Baricitinib for Alopecia Areata
- And more
Plus, discover bonus notable articles from NEJM Catalyst Innovations in Care Delivery and NEJM Evidence.
We hope that you enjoy reviewing the past year with us. Download Notable Articles of 2022 now.